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    Bisoprolol Fumarate Tablets USP 5 mg

    Introduction

    BISOWALK 5 (Bisoprolol Fumarate Tablets USP 5 mg) manufactured by BIOALTUS helps control high blood pressure, heart failure, and irregular heartbeat. It works by slowing the heart rate and lowering blood pressure, making the heart work better. Made with high-quality standards, it ensures safe and effective treatment for heart health.

    BISOWALK 5 is a pharmaceutical product containing Bisoprolol Fumarate, a beta-blocker widely used in the management of hypertension, heart failure, and certain heart rhythm disorders. Manufactured by Biophar Group, a trusted division of Biophar Lifesciences Pvt Ltd, this medication offers a reliable solution for cardiovascular care. When selecting the best PCD/franchisee company, it is crucial to consider quality, regulatory approvals, and market reputation.

    Composition

    Each tablet of BISOWALK 5 contains Bisoprolol Fumarate USP 5 mg as the active ingredient along with pharmaceutical excipients to ensure efficacy and stability.

    Pharmacological Classification

    • Class: Beta-1 Selective Adrenergic Blocker (Beta-blocker)
    • ATC Code: C07AB07

    Mechanism of Action

    Bisoprolol Fumarate selectively inhibits beta-1 adrenergic receptors in the heart, reducing heart rate, myocardial contractility, and cardiac output. This leads to a decrease in blood pressure and heart workload, making it highly effective for treating hypertension and chronic heart failure.

    Indications

    BISOWALK 5 is prescribed for the following conditions:

    1. Hypertension (high blood pressure): helps in lowering blood pressure and reducing cardiovascular risks.
    2. Chronic Heart Failure: Used as part of a combination therapy to improve heart function.
    3. Angina pectoris (chest pain): reduces the oxygen demand of the heart and alleviates symptoms.
    4. Arrhythmias (irregular heartbeat): Helps stabilize heart rhythm by controlling electrical impulses.

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    Dosage and Administration

    • Usual Adult Dose: 5 mg once daily
    • Maximum Dose: Up to 20 mg per day, as prescribed by a physician
    • Administration: The tablet should be taken with or without food and swallowed whole with water.

    Dose Adjustments

    • Mild to Moderate Hypertension: 2.5–5 mg daily
    • Severe Cases of Heart Failure: Titration from 1.25 mg to 10 mg under medical supervision
    • Patients with Renal or Hepatic Impairment: Dose adjustment may be required based on clinical condition

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    Contraindications

    BISOWALK 5 should not be used under the following conditions:

    • Severe bradycardia (slow heart rate)
    • Cardiogenic shock
    • Severe asthma or chronic obstructive pulmonary disease (COPD)
    • Hypersensitivity to Bisoprolol or any excipients in the formulation
    • Uncompensated heart failure

    Warnings and Precautions

    • Use in Asthma or COPD: Caution is advised as beta-blockers may cause bronchospasm.
    • Diabetes: Can mask symptoms of hypoglycemia; blood sugar levels should be monitored regularly.
    • Thyroid Disorders: May mask symptoms of hyperthyroidism.
    • Pregnancy and Lactation: Should be used only if the potential benefits outweigh the risks.
    • Withdrawal: Abrupt discontinuation should be avoided to prevent rebound hypertension or arrhythmias.

    Drug Interactions

    • Other antihypertensives: May cause excessive blood pressure reduction.
    • Calcium Channel Blockers (e.g., Verapamil, Diltiazem): Risk of bradycardia and heart failure.
    • Antiarrhythmic Drugs: These may enhance negative effects on heart rhythm.
    • Insulin and oral hypoglycemic agents can mask hypoglycemia symptoms.
    • NSAIDs: May reduce the antihypertensive effects of bisoprolol.

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    Side Effects

    BISOWALK 5 is well tolerated, but some patients may experience:

    • Common Side Effects: Fatigue, dizziness, headache, bradycardia, hypotension
    • Less Common Side Effects: Sleep disturbances, depression, gastrointestinal discomfort
    • Rare Side Effects: Allergic reactions, bronchospasm, liver enzyme elevation

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    Overdose and Management

    Symptoms of Overdose:

    • Extreme bradycardia
    • Severe hypotension
    • Respiratory distress
    • Acute heart failure

    Treatment Measures:

    • Activated charcoal (if within 1 hour of ingestion)
    • IV fluids and vasopressors for hypotension
    • Atropine for bradycardia
    • Glucagon or beta-agonists for severe cases

    Clinical Studies and Efficacy

    Clinical trials have demonstrated that bisoprolol significantly reduces morbidity and mortality in patients with chronic heart failure and hypertension. Studies have also confirmed its superior tolerability compared to non-selective beta-blockers.

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    Storage and Handling

    • Storage Temperature: Store below 30°C in a dry place, away from moisture and direct sunlight.
    • Packaging: Available in blister packs to maintain stability.
    • Keep out of reach of children.

    Why Choose BISOWALK 5 by Biophar Group?

    • High-quality manufacturing standards: Produced under GMP-certified facilities.
    • Proven Efficacy and Safety: Clinically tested formulation.
    • Trusted Brand: Biophar Group is known for excellence in pharmaceutical innovations.
    • Affordability and accessibility: ensures cost-effective treatment for cardiovascular conditions.

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    Conclusion

    BISOWALK 5 (Bisoprolol Fumarate 5 mg) is a highly effective and well-tolerated medication for hypertension, heart failure, and other cardiovascular disorders. Biophar Group, a division of Biophar Lifesciences Pvt Ltd, ensures that this product meets the highest standards of quality, safety, and efficacy.

    Consult your healthcare provider before starting BISOWALK 5 to ensure the right dosage and suitability for your condition.

    Best PCD Pharma Franchise & Third-party Pharma Manufacturing Company In All Of India

    Contact us for Pharma Franchise and if you want to buy this tablet in bulk quantity      

    Visit Our Website: https://www.biophargroup.com             

    Contact Info: +91-9888871967     

    Email Id: Biophar.purchase@gmail.com              

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