Subaitra-SB (Itraconazole Capsules BP 65 mg, 130 mg) by Biophar Group

Introduction

Subaitra-SB is a high-quality antifungal medication containing Itraconazole as its active ingredient. It is manufactured and marketed by Biophar Group, a division of Biophar Lifesciences Pvt Ltd. This medication is available in two strengths, 65 mg and 130 mg, and is primarily used for treating fungal infections in various parts of the body. Itraconazole is a triazole antifungal that works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby preventing the growth and spread of fungal infections.

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Composition and Available Strengths

• Subaitra-SB 65 mg: Each capsule contains Itraconazole BP 65 mg.
• Subaitra-SB 130 mg: Each capsule contains Itraconazole BP 130 mg.

Uses and Indications

Subaitra-SB is used for the treatment of various fungal infections, including:

1. Dermatophytosis: Fungal infections affecting the skin, nails, and hair.
2. Onychomycosis: fungal infections of the toenails and fingernails.
3. Sporotrichosis: A rare fungal infection caused by Sporothrix schenckii.
4. Blastomycosis: A serious fungal infection affecting the lungs and other body parts.
5. Histoplasmosis: A respiratory fungal infection caused by Histoplasma capsulatum.
6. Aspergillosis: A lung infection caused by the Aspergillus fungus.
7. Candidiasis: Fungal infections caused by Candida species, including oral and vaginal yeast infections.
8. Cryptococcosis: A fungal infection affecting the lungs and central nervous system.

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Mechanism of Action

Itraconazole belongs to the azole class of antifungals and works by inhibiting the enzyme lanosterol 14α-demethylase, which is crucial for the biosynthesis of ergosterol. Ergosterol is an essential component of fungal cell membranes, and its depletion leads to increased permeability and disruption of cellular functions, ultimately causing fungal cell death.

Dosage and Administration

General Guidelines:

• The dosage and duration of treatment depend on the type and severity of the infection.
• Capsules should be taken with food for better absorption.
• Do not chew, crush, or break the capsules; swallow them whole with water.

Recommended Dosage:

• Dermatophytosis & Candidiasis: 100–200 mg per day for 2–4 weeks.
• Onychomycosis: 200 mg once daily for 3 months or pulse therapy (200 mg twice daily for 1 week per month, repeated for 3–4 months).
• Systemic Fungal Infections: 200–400 mg per day, as prescribed by a healthcare professional.
• Aspergillosis & Histoplasmosis: 200–400 mg daily for several months.

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Side Effects

While Subaitra-SB is generally well tolerated, some patients may experience side effects, including:

• Common Side Effects:
  • Nausea and vomiting
  • Diarrhea or constipation
  • Headache
  • Dizziness
  • Abdominal pain
  • Fatigue
  • Skin rashes
• Serious Side Effects (Seek Medical Attention Immediately):
  • Liver problems (jaundice, dark urine, pale stools, fatigue)
  • Heart failure symptoms (swelling in the legs, shortness of breath, rapid weight gain)
  • Severe allergic reactions (rash, itching, swelling, difficulty breathing)

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Storage and Handling

• Store below 25°C in a cool, dry place away from direct sunlight.
• Keep out of the reach of children.
• Do not use expired medication.
• Keep capsules in their original packaging to protect them from moisture.

Advantages of Subaitra-SB

1. Broad-Spectrum Action: Effective against a wide range of fungal infections.
2. High Bioavailability: Absorbed well when taken with food.
3. Pulse Therapy Option: Allows intermittent dosing for onychomycosis, reducing toxicity.
4. Convenient Dosing: Once or twice-daily regimen.
5. Reliable Manufacturer: Manufactured by Biophar Group, a reputed name in pharmaceuticals.

Frequently Asked Questions (FAQs)

Q1: Can I take Subaitra-SB without food?
A: No, it is recommended to take it with food to enhance absorption.

Q2: How long does it take for Itraconazole to show results?
A: Improvement can be seen in a few days, but full treatment duration is necessary to prevent recurrence.

Q3: Can I drink alcohol while taking Itraconazole?
A: Alcohol should be avoided as it increases the risk of liver toxicity.

Q4: Is Subaitra-SB safe for children?
A: Use in pediatric patients should be under strict medical supervision.

Q5: What if my symptoms persist?
A: Consult your doctor if symptoms do not improve within the prescribed duration.

Conclusion

Subaitra-SB, containing 65 mg and 130 mg of itraconazole, is a highly effective antifungal medication used for treating a variety of fungal infections. Manufactured by Biophar Group, this medication is a trusted choice for dermatological and systemic fungal infections. When selecting a PCD/franchisee company, it is essential to choose a branded and trusted franchisee/PCD company that offers innovative solutions like amino acid injections, IVF products, and the latest molecules from Ortho Company. Always consult a healthcare provider for personalized advice and treatment.

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